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Structure-Activity Relationships and Evaluation of 2-(Heteroaryl-cycloalkyl)-1H-indoles as Tauopathy Positron Emission Tomography Radiotracers

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Stehouwer JS, Huang G, Saturnino Guarino D, Debnath ML, Polu A, Geib SJ, Lopresti B, Ikonomovic MD, Mason N, Mach RH, Mathis CA.

J Med Chem. 2025 Mar 27;68(6):6462-6492. doi: 10.1021/acs.jmedchem.4c02988. Epub 2025 Mar 11.

2025

PMID

40068019

https://doi.org/10.1021/acs.jmedchem.4c02988

PSP/CBD

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Structure-Activity Relationships and Evaluation of 2-(Heteroaryl-cycloalkyl)-1H-indoles as Tauopathy Positron Emission Tomography Radiotracers
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